Cell Signal Integration Lab

Our Lab is broadly involved in applying state-of-the-art experimental, computational, and theoretical techniques to investigate the structure, function, and dynamics of 14-3-3 complexes.
We are loacated @Instituto de Histologia y Embriologia de Mendoza. CONICET Universidad Nacional de Cuyo. MENDOZA - ARGENTINA.

Research

We have several lines of research about 14-3-3 protein family, from cell biology to computational biology including biochemistry

People

In our group there are 10 people between researchers and technicians trained and in formation

Publications

More than 30 publications since 2006

Why us?

Watch the video on how 14-3-3 works! by Exequiel

Research

We have several lines of research about 14-3-3 protein family, from cell biology to computational biology including biochemistry

Publications

Selected publications, for a full list please go to the link at home/why us

» Frontini-López, Y. R., Gojanovich, A. D., Del Veliz, S., Uhart, M., & Bustos, D. M. (2021). 14-3-3b isoform is specifically acetylated at Lys51 during differentiation to the osteogenic lineage. Journal of Cellular Biochemistry, 122(12), 1767–1780.

» Del Veliz, S., Rivera, L., Bustos, D. M., & Uhart, M. (2021). Analysis of SARS-CoV-2 nucleocapsid phosphoprote in N variations in the binding site to human 14-3-3 proteins. Biochemical and Biophysical Research Communications, 569, 154–160.

» Sluchanko, N. N., & Bustos, D. M. (2019). Intrinsic disorder associated with 14-3-3 proteins and their partners. Progress in Molecular Biology and Translational Science, 166, 19–61.

» Uhart, M., Flores, G., & Bustos, D. M. (2016). Controllability of protein-protein interaction phosphorylation-based networks: Participation of the hub 14-3-3 protein family. Scientific Reports, 6(1), 1–11.

Services

We do services trought ‘servicios tecnológicos de alto nivel’ - STAN CONICET. Please send us a message if you have any question

Biological data mining & databases

We development databases

Protein design

Protein feature discovery

Lab Mates

We are always looking for students at any level. If you are interested in our research please contact us.

Person1

Prof Dr Diego M Bustos

Professor / Researcher

Resercher at CONICET; Postdoc NIH (USA), CNRS (France)

Person2

Dra Marina Uhart

Researcher / Cell studies coordinator

Resercher at CONICET; Postdoc NIH (USA)

Person2

Dr Exequiel Barrera

Researcher / Computational studies coordinator

Resercher at CONICET; Postdoc IP Montevideo (Uruguay)

Person3

MSc Lautaro Rivera

PhD Student (FFyBioq - UBA / CONICET)

Person3

MSc Sergio Müller

PhD Student (FFyBioq - UBA / CONICET)

Person3

MSc Laura Pinto

PhD Student (FCEN - UNCUyo / CONICET)

Person3

MSc Beatriz Piniella

PhD Student (FCEN - UNCUyo / CONICET)

Person3

MSc Lorena Fontana

PhD Student (PROBIOL - UNCUyo / CONICET)

Person3

MSc Jonatan Aguilera

PhD Student (FCEN - UNCUyo / ANPCyT)

Stats

34 Finished projects
40 Publications
1302 Cups of coffee, and counting
20 Former Students

Pictures of the group

There were many moments of fun and to be proud of

Get in touch

We are located in Mendoza at the Parque Gral San Martin, UNCUyo Campus